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A case report exploring the use of subcutaneous Botox for the treatment of neuropathic pain in active head and neck cancer

Year: 2026

Type: article

Abstract: Patients with head and neck cancer commonly experience severe neuropathic pain. This pain is often challenging to treat and may be refractory to standard analgesic approaches. We describe the use of subcutaneous Botox injections to manage pain in such a patient. A patient with poorly differentiated carcinoma of the right base of skull with perineural invasion presented to the pain clinic with intractable facial pain. Subcutaneous Botox injections were performed. The patient experienced a significant reduction in the intensity of her pain following subcutaneous Botox injections. Subcutaneous Botox injections represent a safe and effective option for patients with head and neck cancer experiencing neuropathic pain refectory to standard analgesic medications.

Source: Pain Management

DOI: 10.1080/17581869.2026.2660148

Authors: Ellie I. Davidson, Kee Howe Wong, Smita L. A. Almeida, Matthew R. D. Brown

Institutions: Royal Marsden Hospital, Institute of Cancer Research, Institute of Cancer Research

Language: English

Topic: Pain Management and Opioid Use

Subfield: Anesthesiology and Pain Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7155205171

FWCI:

Cites: 20

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