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Ketone ester supplementation reduces age-associated B cell activation in aged mice without impairing antibody responses

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Year: 2026
Type: preprint
Source: Research Square
DOI: 10.21203/rs.3.rs-10756850/v1
Authors: Ariel Adkisson-Floro, Ritesh Tiwari, Mitsunori Nomura, Rebeccah R. Riley, Ryan Kwok, Durai Sellegounder, Mir M. Khalid, Herbert G. Kasler, John C. Newman, Eric Verdin
Institution: Buck Institute for Research on Aging
Language: English

Topic: Diet and metabolism studies
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: green

Funders: Hevolution Foundation, Buck Institute for Research on Aging, National Institutes of Health, National Institute on Aging
Awards: G1163773571, Geroscience metabolites beta-hydroxybutyrate and NAD+ linking inflammation and neuroenergetic failure in delirium, Cellular senescence and Associated Lysosomal Dysfunction in Immune Aging, G5965726837, Mechanisms of the signaling metabolite β-hydroxybutyrate in Alzheimer's disease and the aging brain, USC-Buck Geroscience Training in the Biology of Aging, Training in Basic Research on Aging and Age-Related Disease
OpenAlex ID: W7155350872
Cites: 63
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