Work

A novel diagnostic and treatment paradigm for Streptococcus pasteureus infection in neonates: a case study

Year: 2026

Type: article

Abstract: INTRODUCTION: Streptococcus pasteurianus (S. pasteurianus) is a highly invasive bacteria, which is uncommon in neonates. Its main clinical manifestations include invasive sepsis and meningitis. If not detected in time, prognosis is often poor. CASE PRESENTATION: We presented a case of a 16-day-old female admitted to our hospital with groans and fever accompanied by dyspnoea. Two non-specific inflammatory markers were elevated. Laboratory markers suggested the presence of meningitis. A second-generation sequencing of cerebrospinal fluid suggested an S. pasteurianus infection. Simultaneously, the patient's coagulation studies indicated a hypercoagulable state. The child was successfully treated with anti-infective therapy and anticoagulation therapy and was discharged from the hospital without complications. CONCLUSION: For patients with similar conditions, we recommend pathogens screening to target the etiology of the disease and monitor coagulation function tests during systemic inflammatory reactions.

Source: BMC Pediatrics

DOI: 10.1186/s12887-026-06880-w

Authors: Shouliang Jiang, Qi He, Li Zhang, Jun Tang

Institutions: Sichuan University, West China Second University Hospital of Sichuan University

Language: English

Topic: Neonatal and Maternal Infections

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,090