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Eculizumab for Pediatric Hematopoietic Cell Transplant–Associated Thrombotic Microangiopathy: Real-World Response Rates, Predictors of Poor Response, and an Optimal Time Point for Treatment Response Assessment

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Year: 2026
Type: article
Study design: Observational Study
Source: Transplantation and Cellular Therapy
DOI: 10.1016/j.jtct.2026.04.026
Authors: Michelle L. Schoettler, Geoffrey Cheng, Christine S. Higham, Christopher C. Dvorak, Cassandra Rush, Hemalatha G. Rangarajan, Majed Al-Nazer, Veronika Polishchuk, Sonali Chaudhury, Leslie Lehmann, Christine Duncan, Miki Nishitani, Haig Manougian, Seth Rotz, Joel Ofori, Erin Frost, Jeremy Orbodo, Kathleen Spencer, Ellen Kenney, Satheesh Chonat, Joseph Chewning, Caitlin Moore, Adrianna Westbrook, Kirsten M. Williams
Institutions: Emory University, Children's Healthcare of Atlanta, University of California, San Francisco, Nationwide Children's Hospital, The Ohio State University, Lurie Children's Hospital, Boston Children's Hospital, Dana-Farber Cancer Institute, Cleveland Clinic, Children's of Alabama
Language: English

Topic: Complement system in diseases
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funder: National Cancer Institute
Award: Research Training in Childhood Cancer
OpenAlex ID: W7155489043
FWCI: 5.28
Cites: 41
Cited by: 2
Related to: 10
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