Work

Health-Related Quality of Life and Associated Factors Before and After Coronary Artery Bypass Grafting: A Multicentre Prospective Study in Cyprus

Year: 2026

Type: article

Abstract: OBJECTIVES: Coronary artery bypass grafting (CABG) improves survival in coronary artery disease (CAD), but its impact on health-related quality of life (HRQOL) remains variable. This study aimed to evaluate changes in HRQOL and associated factors before and after CABG. METHODS: This prospective multicentre study, conducted across 3 hospitals in Cyprus, included patients undergoing elective CABG. Health-related quality of life was assessed using the MacNew questionnaire preoperatively and at 3 and 6 months postoperatively. Associations with demographic and clinical factors, including age, gender, postoperative arrhythmias, left ventricular ejection fraction, and type of surgery, were examined. Non-parametric methods were applied due to non-normal data distribution. RESULTS: Health-related quality of life declined at 3 months compared with baseline (5.03 ± 1.02 vs 4.75 ± 1.00; P = .015), but improved significantly at 6 months (5.99 ± 0.67), exceeding preoperative levels. Male gender was associated with higher HRQOL scores at both follow-up time points (P = .011 and P = .009). No significant differences were observed by age, postoperative arrhythmia, left ventricular ejection fraction, or type of surgery. CONCLUSIONS: Health-related quality of life declined early after CABG but improved significantly by 6 months, exceeding baseline levels. Male gender was associated with higher HRQOL scores. These findings support the value of incorporating HRQOL assessment into routine postoperative care. TRIAL REGISTRATION: Thai Clinical Trials Registry (TCTR), ID: TCTR202247. URL: https://www.thaiclinicaltrials.org/.

Source: Interdisciplinary CardioVascular and Thoracic Surgery

DOI: 10.1093/icvts/ivag126

Authors: Kyriakos Alexandrou, Nicos Middleton, Maria Kyranou, Pavlos Sarafis

Institutions: Cyprus University of Technology, University of Thessaly

Language: English

Topic: Cardiac and Coronary Surgery Techniques

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,258