Oesophageal necrosis after impaction as a proposed cause of markedly elevated serum creatine kinase activity in a juvenile cat
Year: 2026
Type: article
Study design: Case Report
Abstract: Case summary A 21-week-old, male castrated domestic mediumhair cat presented with a history of acute, severe regurgitation. No abnormalities were detected on physical examination. Initial serum biochemistry identified marked elevation in creatine kinase (CK) (905,409 U/l, reference interval [RI] 50–400), which persisted after 24 h of supportive care (32,491 U/l, RI 50–400). Serology for Toxoplasma gondii was negative. Radiography and ultrasound found severe caudal oesophageal impaction. The kitten was euthanased; a post-mortem examination confirmed oesophageal food impaction and severe, focally extensive oesophageal necrosis. The underlying cause of the oesophageal impaction was not definitively determined. Other than the oesophageal necrosis, there were no other autopsy findings to explain the elevated CK. Relevance and novel information Oesophageal muscle necrosis may be associated with severe elevations in CK concentrations and oesophageal disease should be considered if there is no obvious trauma, polymyopathy or cardiac disease in feline patients with markedly elevated CK.
Authors: Hannah K Lobegeier, Panayiotis Loukopoulos, Robert BS Turner
Institution: The University of Melbourne
Language: English
Subfield: Small Animals
Field: Veterinary
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $700
OpenAlex ID: W7155634716