Work

The Golden Ratio of Resilience: A Software Reframe for Mitochondrial Enlightenment and Cellular Longevity

Year: 2026

Type: article

Abstract: A cybernetic pharmacology framework built on a 70:30 SBMA‑b‑CBMA “Golden Ratio” polymer architecture, designed to restore mitochondrial resilience through a dual‑condition AND‑gate. The system maps mitochondrial distress signals—membrane depolarization ΔΨm and ROS‑driven stiffness modulation α([ROS])—onto a bistable potential U(x)=α2x2+β4x4, triggering payload release only when the computed barrier ΔU

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.19769969

Author: Feeney, Don

Language: English

Topic: Mitochondrial Function and Pathology

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W7155644372

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