Nephrogenic Systemic Fibrosis (NSF): An assessment of perception and practice of Nigerian MRI Radiographers.
Year: 2026
Type: article
Study design: Observational Study
Abstract: Background: Nephrogenic Systemic Fibrosis (NSF) is a serious fibrotic disorder seen in patients with kidney impairment, triggered by gadolinium-based contrast agents (GBCAs) used in MRI. It manifests with skin thickening, joint contractures, and potential organ involvement, with no available cure. Linear GBCAs have higher associated risks, prompting global regulatory restrictions. As MRI utilization increases in Nigeria, the level of radiographers’ awareness and adherence to NSF prevention guidelines remains unclear. Assessing their training and clinical practices is essential for improving patient safety and aligning with international standards. Objective: To assess the perception, knowledge, and clinical practices of MRI radiographers regarding NSF and GBCA safety. Method: A descriptive cross-sectional study was conducted to evaluate knowledge, awareness, perception, and practices regarding NSF and GBCA safety among Nigerian MRI radiographers. Participants involved in patient screening and GBCA administration across multiple centers were surveyed using a structured, pre-tested questionnaire adapted from validated instruments. Data analysis employed descriptive and inferential statistics to assess understanding and compliance with NSF prevention protocols. Ethical approval and participant confidentiality were strictly maintained. Results: Among 42 surveyed Nigerian MRI radiographers, 78.4% were aware of NSF, but only 37.8% demonstrated comprehensive knowledge of prevention guidelines. Overall knowledge was adequate; however, notable gaps existed concerning gadolinium contrast risks and renal function markers. Weight-based gadolinium dosing was commonly practiced. Renal screening protocols varied, being more consistently applied in private healthcare facilities. Radiographers’ experience and clinical role significantly influenced NSF knowledge, while the practice environment predicted adherence to safety measures. Conclusion: MRI radiographers demonstrate general awareness of NSF, but gaps persist in guideline familiarity and standardized renal screening practices. Strengthening education, institutional protocols, and regulatory oversight may enhance patient safety and reduce NSF risk.
Source: JRRS
Institution: Osun State University
Language: English
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W7155718646
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