O 2 ‐Mediated Cu‐Catalyzed Dehydrogenative Sulfilimination of Tyrosines and Bioactive Phenols
Year: 2026
Type: article
Abstract: The bioconjugation of unmodified native peptides, in particular at their tyrosine units with the dehydrogenative phenochalcogenazination reaction, has attracted much attention lately due to potential click type applications. In our quest to bring this oxidative coupling concept beyond phenothiazines and its derivatives, we report herein the case of sulfenamides and their mild O 2 ‐mediated Cu‐catalyzed dehydrogenative sulfilimination of diverse bioactive phenols.
Source: Advanced Synthesis & Catalysis
DOI: 10.1002/adsc.70420
Authors: Fang Xiao, Frederic W. Patureau
Institution: RWTH Aachen University
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $4,650
OpenAlex ID: W7155879329