Real-world drug utilisation of nintedanib and pirfenidone for interstitial lung disease in Singapore
Year: 2026
Type: article
Study design: Observational Study
Abstract: Antifibrotic therapies such as nintedanib and pirfenidone have transformed interstitial lung disease (ILD) treatment, representing a significant advancement in managing progressive fibrosing conditions. While these agents are used across Asia, their use in Southeast Asia, for example in Singapore, Malaysia or Indonesia, remains significantly under-represented in literature. To address these knowledge gaps in real-world use of antifibrotics among Southeast Asian population, we conducted a retrospective drug use evaluation at the ILD subspecialty service in Tan Tock Seng Hospital in Singapore from January 2016 to October 2024, with the aim to evaluate the usage patterns and clinical outcomes of nintedanib and pirfenidone in patients with ILD.
Authors: Tingfeng Lee, Yi Jing Lim, Andrew Yunkai Li, Ziqin Ng, Zhikui Chrystal Huang, Gin Tsen Chai
Institutions: Tan Tock Seng Hospital, National Healthcare Group
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7155938640