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Unilateral proptosis as the manifestation of euthyroid Graves orbitopathy: A case report

Year: 2026

Type: article

Abstract: RATIONALE: To report a case of Euthyroid Graves' disease with Unilateral eye involvement and its diagnostic and management challenges. PATIENT CONCERNS: A 36-year-old female with left eye proptosis. DIAGNOSES: CECT and MRI reported the proptosis of the left eye with thickening of the left extraocular muscles without the involvement of the tendons, without a focal lesion, with mild hyperintensity and mild diffuse enhancement representing unilateral thyroid ophthalmopathy. INTERVENTIONS: CECT and MRI for the diagnosis. IV methylprednisolone for the management. OUTCOMES: Complete resolution of symptoms by 6 months. LEARNINGS: 1) Although commonly hyperthyroid, patients with Graves' disease may be euthyroid. 2) Graves' orbitopathy can affect the unilateral eye. 3) Long-term follow-up and joint endocrine and ophthalmology teamwork required for effective management.

Source: Medicine

DOI: 10.1097/md.0000000000048416

Authors: Simran Rauniyar, Milan Pokhrel, Sonam Dhenga, Ganesh Chaudhary, Bibek Shrestha

Institutions: Tribhuvan University, Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University Teaching Hospital

Language: English

Topic: Ophthalmology and Eye Disorders

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,950