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Laboratory Assessment and Clinical Outlook for Ex Vivo -Produced Human Platelets and Megakaryocytes from Stem Cell Sources

Year: 2026

Type: article

Abstract: circulation of platelet products. Initial implementation will likely focus on high-value applications, such as transfusion for alloimmunized patients, before broader adoption. The long-term goal is to replace the vulnerable donor-dependent system with on-demand production of standardized, pathogen-free, and universally compatible platelets.

Source: Annals of Laboratory Medicine

DOI: 10.3343/alm.2025.0687

Authors: Kyoung Mi Kim, Koudai I. Albaira, Yong Gon Cho, Hyun Ok Kim, Hyung Jin Kim, Soon Sung Kwon, Jaecheol Lee, Dae-Hyun Ko, Sinyoung Kim, Seung Yeob Lee

Institutions: Jeonbuk National University Hospital, Jeonbuk National University, Yonsei University, Yonsei University Health System, Sungkyunkwan University, Asan Medical Center, University of Ulsan

Language: English

Topic: Platelet Disorders and Treatments

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Ministry of Trade, Industry and Energy, Ministry of Food and Drug Safety, Ministry of Health and Welfare, National Research Foundation of Korea, Ministry of Science and ICT, South Korea, Jeonbuk National University

Awards: G1093964719, G1106278241, G3302768887, G3706393791, G5086035360, G5391573974, G6575182237, G7381596740, G7415092590, G8506485888

OpenAlex ID: W7156102771

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