Work

Multiscale Simulations Reveal Distal Allosteric Reprogramming of Pocket Dynamics and Dual Hydrolytic Pathways in Engineered Methyl Parathion Hydrolase

Year: 2026

Type: article

Source: The Journal of Physical Chemistry B

DOI: 10.1021/acs.jpcb.6c01732

Authors: Xiaoyuan Liu, Yuzhuang Fu, Jun Yu, Nan Lv, Zhiyang Zhang, Yuan Zhao, Yubing Si, Zexing Cao

Institutions: Xiamen University, China Pharmaceutical University, State Key Laboratory of Natural Medicine, Henan Normal University, Huzhou College, Henan University, First Affiliated Hospital of Henan University, Zhengzhou University

Language: English

Topic: Protein Structure and Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funders: National Natural Science Foundation of China, Natural Science Foundation of Henan Province

Awards: G1289185710, G5002692191

OpenAlex ID: W7156116676

FWCI: 1.842

Cites: 65

Cited by: 1

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