Work

Realization of long axial field-of-view PET technology in the clinic and research environment

Year: 2026

Type: article

Abstract: Long axial field-of-view (AFOV) PET-CT instruments have significantly higher sensitivity than conventional PET scanners, allowing for reduced scan time and/or reduced radiotracer dose. The long axial coverage also permits multiorgan dynamic imaging with fine temporal sampling. In this article, we discuss how the technical advantages of long AFOV PET instruments are being realized in the clinic and exploited in research studies. We describe some practical considerations for these systems in the clinic, as well as their benefits beyond the clinic. We consider alternate scanner designs to mitigate the high cost of long AFOV systems currently in use and describe how deep learning is being applied to long AFOV PET studies to reduce image noise, allowing for even shorter scans to minimize motion, aid in dynamic imaging applications, and image generation. We conclude with some ideas on what future developments may be on the horizon for long AFOV PET.

Source: British Journal of Radiology

DOI: 10.1093/bjr/tqag096

Authors: Florence M Muller, Margaret E Daube-Witherspoon, Elizabeth J Li, Austin R Pantel, Joel S Karp

Institutions: Ghent University, University of Pennsylvania

Language: English

Topic: Medical Imaging Techniques and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,005