Year: 2026
Type: article
Study design: Systematic Review
Abstract: Spiradenomas are rare adnexal neoplasms that clinically mimic other cutaneous entities, such as epidermoid cysts and basal cell carcinomas. Although ultrasound diagnosis of common cutaneous tumors has significantly evolved over the last decades, the sonographic presentations of spiradenomas have been scarcely described. This study includes a case report and systematic review of previously reported sonographic characteristics of spiradenomas. A comprehensive search of the Pubmed/MEDLINE database identified studies with histological confirmation and ultrasound characterization of spiradenomas. Eight articles, comprising seven case reports and one case series with eight cases, were included. Data on clinical, demographic and sonographic features were extracted and analyzed. On B-mode ultrasound, spiradenomas appeared as well-defined, multilobulated, heterogeneous, hypoechoic masses located within the dermis and/or hypodermis, with posterior acoustic enhancement. Color Doppler imaging showed increased intralesional vascularization without anarchic pattern. The identified features helped differentiate spiradenomas from similar conditions, potentially reducing misdiagnoses, and optimizing management.
Source: Journal of Clinical Ultrasound
DOI: 10.1002/jcu.70256
Authors: Emilio Garcia‐Mouronte, Maria‐Elena de las Heras Alonso, Luis Alonso‐Mtz de Salinas, Emilio Berna‐Rico, Pablo Fernandez‐Gonzalez
Institution: Hospital Universitario Ramón y Cajal
Language: English
Topic: Cancer and Skin Lesions
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7156891702