Work

Primary hepatic neuroendocrine tumour in a child

Year: 2026

Type: article

Abstract: ABSTRACT: Primary hepatic neuroendocrine tumour (PHNET) is an exceptionally rare neoplasm, accounting for approximately 0.3% of all neuroendocrine tumours. It presents with non specific clinical and radiological features, making pre operative diagnosis difficult. Differentiation from other paediatric liver lesions, such as hepatoblastoma, haemangioma and hepatocellular carcinoma, is challenging. We report the rare case of PHNET in a 9 year old boy who presented with abdominal pain and vomiting. Routine laboratory investigations, including liver function tests and serum alpha fetoprotein levels, were within the normal limits. Radiological evaluation suggested a diagnosis of sclerosed hepatic haemangioma. Definitive diagnosis was established by histopathological examination and immunohistochemistry. Surgical resection was performed, which remains the mainstay of treatment. The post operative course was uneventful and regular follow up. This case highlights the diagnostic difficulty of PHNET and underscores the importance of histopathological evaluation for accurate diagnosis and appropriate management.

Source: Journal of Minimal Access Surgery

DOI: 10.4103/jmas.jmas_587_25

Authors: Sanjay Kumar, Akanksha, Khushi, Pooja Rathee, Sant Prakash Kataria, Sunita Singh

Institutions: Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Pandit Bhagwat Dayal Sharma University of Health Sciences

Language: English

Topic: Neuroendocrine Tumor Research Advances

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $200