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Kidney Metastasis From Adenoid Cystic Carcinoma of the Submandibular Gland: A Case Report and Literature Review

Year: 2026

Type: article

Abstract: Adenoid cystic carcinoma (ACC) of the salivary glands is characterized by perineural invasion, local recurrence, and distant metastasis, predominantly to the lungs; however, unusual metastatic sites have also been reported. Renal metastasis from primary ACC is clinically rare. To the best of our knowledge, there have been only 13 cases of ACC metastasizing to the kidney. Here, we present an additional case of left renal metastases originating from a left submandibular gland ACC. In this report, we describe a 38-year-old male who developed left renal metastases 30 months after completing postoperative radiotherapy for ACC of the left submandibular gland. We also provide a review of the literature on renal metastases from ACC, highlighting its rarity, clinical presentation, radiological findings, and management strategies.

Source: Cureus

DOI: 10.7759/cureus.107848

Authors: Renda Alhabib, Chaker Zaidi, Nuran Baabbad, Ibrahim Alotain

Institution: King Fahad Specialist Hospital

Language: English

Topic: Salivary Gland Tumors Diagnosis and Treatment

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7157259980