Correction of hypoxemia and hypoglycemia restores muscle mitochondrial respiration and remodels mitochondrial proteome in growth-restricted sheep fetuses
Year: 2026
Type: erratum
Abstract: Using a sheep model of placental insufficiency, we showed that prenatal oxygen and glucose supplementation improved mitochondrial respiration and partially normalized mitochondrial proteomic profiles in growth-restricted fetal skeletal muscle. These findings highlight that targeted prenatal correction of hypoxemia and hypoglycemia can mitigate mitochondrial deficits associated with fetal growth restriction.
Institutions: University of Arizona, University of Colorado Anschutz
Language: English
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: G2368114838, G9000085806
OpenAlex ID: W7158985947