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Visualizable, AKR1C3-Activated Small-Molecule Antitumor Drug Conjugates with Ultra-Low Systemic Toxicity

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Year: 2026
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.5c03834
Authors: Ningfang Kang, Shuainan Liu, Xiaoyu Li, Ruxiang Luo, Wenyan Chen, Chongzhao Ran, Peng Wang, Jing Yang
Institutions: China Pharmaceutical University, Harvard University, Massachusetts General Hospital, Athinoula A. Martinos Center for Biomedical Imaging
Language: English

Topic: Synthesis and biological activity
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Basic Research Program of Jiangsu Province
Awards: G3019211631, G4095651867, G6215628462, G7926085081
OpenAlex ID: W7159956561
FWCI: 5.392
Cites: 40
Cited by: 3
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