Work

Multiomic Profiling of 85 iPSC Lines from Familial Dementia Reveals Cellular Diversity and Regulators of Organoid Development

Year: 2026

Type: preprint

Source: SSRN Electronic Journal

DOI: 10.2139/ssrn.6874773

Authors: Le Qi, Taylor Bertucci, Susan Borden, Brigitte L. Arduini, Steven Lotz, Kathryn Bowles, Alison Goate, Celeste M. Karch, Sally Temple, Daniel H Geschwind

Institutions: University of California, Los Angeles, Neural Stem Cell Institute, UK Dementia Research Institute, University of Edinburgh, Icahn School of Medicine at Mount Sinai, Washington University in St. Louis

Language: English

Topic: Pluripotent Stem Cells Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute on Aging, National Institute of Neurological Disorders and Stroke

Awards: Cell Type and Regional Vulnerability in Frontotemporal Dementia, G9000088477, G9000110034, G9000300405, G9000351357, Alzheimer's Disease Research Center, iPSC-based Model to Study Frontotemporal Dementia Due to MAPT Mutation

OpenAlex ID: W7160077008

Cites: 142

Cited by:

Related to: