Elevated target expression by dual PD-L1 and 4-1BB engagement is associated with 89 Zr-PD-L1x4-1BB bispecific Mabcalin tumor uptake
Year: 2026
Type: article
Abstract: The biodistribution of mPD-L1xh4-1BB is specific, dose-dependent, and associated with the elevated target expression resulting from dual PD-L1 and 4-1BB engagement.
Source: Theranostics
DOI: 10.7150/thno.123930
Authors: Claudia A.J. van Winkel, Xiaoyu Fan, Danique Giesen, Glenn Gauderat, Steven de Jong, Thomas Jaquin, Wim Timens, Agathe Lepissier, Marleen Richter, Stefan Grüner, Nicole Andersen, Laurent Laboureur, Lucia Pattarini, Helene Lelièvre, Elisabeth G.E. de Vries, Aizea Morales-Kastresana, Marjolijn N. Lub-de Hooge
Institutions: University Medical Center Groningen, University of Groningen
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,671
OpenAlex ID: W7160094363
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