Work

Case report: A rare case of retroperitoneal mixed type unicentric Castleman disease

Year: 2026

Type: article

Abstract: Objective: To enhance the understanding, diagnosis, and management of retroperitoneal mixed type unicentric Castleman disease. Methods: This report describes a case of retroperitoneal mixed type unicentric Castleman disease managed at our institution. The clinical presentation, histopathological characteristics, and therapeutic approach are detailed. A discussion regarding the current status of diagnosis, management, and prognosis is provided, supplemented by a review of the relevant literature. Results: A 52-year-old female was admitted with a chief complaint of "frequent urination for over 6 months." A retroperitoneal mass was identified. The patient underwent laparoscopic excision of the retroperitoneal mass. Postoperative pathological examination confirmed the diagnosis of mixed type unicentric Castleman disease. The patient's postoperative recovery was uneventful, and she remains under close follow-up surveillance. Conclusion: Retroperitoneal mixed type unicentric Castleman disease is clinically uncommon and possesses distinctive histopathological features. Awareness of this entity needs to be heightened.

Source: Frontiers in Oncology

DOI: 10.3389/fonc.2026.1796146

Authors: Jiajie Zhang, Jian Zhang, Jinhao Liu, Panying Zhang, Shoubin Li

Institutions: Hebei North University, Hebei General Hospital

Language: English

Topic: Lymphadenopathy Diagnosis and Analysis

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801