Work

Redox-responsive Fe( ii )/Fe( iii ) MRI probes with pentadentate or hexadentate macrocyclic ligands

Year: 2026

Type: article

Abstract: Redox-responsive Fe( ii )/Fe( iii ) MRI probes are activated by micromolar peroxide concentrations relevant to physiological conditions. Complexes with hexadentate versus pentadentate ligands show different reactivity towards peroxide and O 2 .

Source: Inorganic Chemistry Frontiers

DOI: 10.1039/d6qi00660d

Authors: Deepak Krishnan Balaji, Joseph A. Spernyak, Matthew R. Crawley, Janet R. Morrow

Institutions: University at Buffalo, State University of New York, Roswell Park Comprehensive Cancer Center

Language: English

Topic: Molecular Sensors and Ion Detection

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Funders: National Science Foundation, Roswell Park Cancer Institute

Awards: G1010591873, Responsive Iron MRI probes with Enhanced Relaxivity