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Metastatic Malignant Melanoma Mimicking Pancreatic Adenocarcinoma

Year: 2026

Type: article

Abstract: Malignant melanoma is an aggressive cutaneous malignancy with a high propensity for lymphatic and distant metastasis. While it commonly spreads to lymph nodes, lungs, brain, liver, and the gastrointestinal tract, pancreatic involvement is generally rare, occurring in less than 1% of cases. We report a case of metastatic melanoma initially misdiagnosed as pancreatic adenocarcinoma. This case underscores the importance of maintaining a broad differential, obtaining tissue diagnosis, and using immunohistochemistry to avoid diagnostic anchoring and ensure accurate identification of metastatic melanoma.

Source: ACG Case Reports Journal

DOI: 10.14309/crj.0000000000002119

Authors: Sneh Sonaiya, Alexandra Jianu, Nicholas Jianu, Namrita George, Pei Xue, Rajan Amin, Vignan Manne

Institutions: University of Nevada, Las Vegas, Lake Erie College of Osteopathic Medicine

Language: English

Topic: Cutaneous Melanoma Detection and Management

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7160493070

FWCI: 2.778

Cites: 19

Cited by: 1

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