Work

Development of a highly conjugated chromophore for precise concentration determination of N(CH3)4OH and N(C4H9)4OH

Year: 2026

Type: article

Abstract: Tetramethylammonium hydroxide (TMAH) is a highly caustic organic base extensively utilized in semiconductor and display manufacturing processes, including photoresist development, silicon etching, and cleaning procedures. This study introduces a novel spectrophotometric method utilizing a dye with a benzophenone moiety, enabling the detection and quantification of TMAH over a wide concentration range with minimal sample preparation. Traditional concentration measurement methods include titration with standard acid solutions and ICP spectroscopy, yet these approaches can be time-consuming, require expensive equipment, or lack rapid on-site assessment. This research indicates that colorimetric properties of new organic compound depending on the concentration of target molecules, which offers a simple, cost-effective, and accurate alternative for the detection of alkali chemical concentration. • New conjugated system was designed and synthesized for a colorimetric indicator. • The detection condition for the quantification of alkali chemicals was systematically investigated. • Precise determination of alkali concentration was carried out in natural water media. • Hazardous alkali, tetramethylammonium hydroxide, was quantified.

Source: Results in Chemistry

DOI: 10.1016/j.rechem.2026.103408

Authors: Hyejin Kim, Haeri Lee

Institution: Hannam University

Language: English

Topic: Molecular Sensors and Ion Detection

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,870

Funders: Hannam University, Ministry of Trade, Industry and Energy, Korea Institute for Advancement of Technology