Self-rated health and mental health before and during the early phase of the COVID-19 pandemic in Germany: the population-based German National Cohort (NAKO) study
Year: 2026
Type: article
Study design: Observational Study
Abstract: BACKGROUND: The COVID-19 pandemic and accompanying social distancing measures might have caused adverse health consequences. We aimed to describe changes in participants' self-rated health and mental health (depression, anxiety, and stress), and investigate factors associated with them. METHODS: We collected data from the German National Cohort (NAKO). We first described changes in participants' self-rated health and mental health from the baseline examination (1 to 6 years earlier) to the early phase of the COVID-19 pandemic. We then applied the multinomial logistic regression model (self-rated health) and the quantile regression model (mental health) to investigate the potential factors associated with the health status and changes. RESULTS: After a median of 3.1 [2.1, 4.1] years from baseline to the early pandemic phase (N = 91,809), 39.3% of participants with good health and 69.7% with less good health status at baseline reported better health. However, the percentage of participants with high depression, anxiety, and stress scores (≥ 10) increased from 6.2%, 4.1%, and 4.3% to 8.6%, 5.6%, and 10.1%, respectively. In the multivariable models, we found that being younger, being male, highly educated, being employed, having higher life satisfaction at baseline, being more physically active, drinking heavily, and experiencing improved anxiety symptoms were associated with improved self-rated health. In contrast, smoking and having mental health disorders were all associated with worse self-rated health. Our results showed that being younger, being female, smoking, drinking heavily, and drinking more since baseline were associated with higher depression scores. Having had a coronavirus test was associated with worse self-rated health and more severe anxiety and stress. CONCLUSIONS: During the early COVID-19 pandemic, many participants experienced improvements in self-rated health but suffered deterioration in mental health and physical activity engagement. Female participants, those who were physically inactive, and those with pre-existing mental disorders were more likely to report poorer health.
Source: BMC Public Health
Authors: Yue Xi, Thomas Keil, Lilian Krist, Tobias Pischon, Ilais Moreno Velásquez, Matthias B Schulze, Wolfgang Ahrens, Hajo Zeeb, Oliver Kuß, Tamara Schikowski, Börge Schmidt, Andreas Stang, Alexandra Nieters, Rafael Mikolajczyk, Janka Massag, Volker Harth, Nadia Obi, Anne C Hallet, Carolina J. Klett-Tammen, Wolfgang Lieb, Markus Löffler, Rudolf Kaaks, Till Bärnighausen, André Karch, Klaus Berger, Muhammad Nasir Khan Khattak, Claudia Meinke-Franze, Michael Leitzmann, Beate Fischer, Hermann Brenner, Bernd Holleczek, Susanne Rospleszcz, Annette Peters
Institutions: Helmholtz Munich, Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie, Ludwig-Maximilians-Universität München, University of Würzburg, Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit, Charité - Universitätsmedizin Berlin, Max Delbrück Center, University of Potsdam, German Institute of Human Nutrition, Leibniz Institute for Prevention Research and Epidemiology - BIPS, University of Bremen, Düsseldorf University Hospital, Deutsches Diabetes-Zentrum e.V., Heinrich Heine University Düsseldorf, Leibniz Institute of Environmental Medicine, University of Duisburg-Essen, University of Freiburg, University Medical Center Freiburg, Deutsches Zentrum für Psychische Gesundheit, Martin Luther University Halle-Wittenberg, University Medical Center Hamburg-Eppendorf, Medizinische Hochschule Hannover, Helmholtz Centre for Infection Research, Christian-Albrechts-Universität zu Kiel, Leipzig University, German Cancer Research Center, University Hospital Heidelberg, University of Münster, Universitätsmedizin Greifswald, Universität Greifswald, University of Regensburg, Krebsregister Saarland
Language: English
Topic: COVID-19 and Mental Health
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Open Access status: gold
Estimated APC paid: $3,290
OpenAlex ID: W7160636775
