A Comparison of Preeclampsia Screening Using Clinical Risk Factors and the Fetal Medicine Foundation Algorithm
Year: 2026
Type: article
Abstract: Aspirin can prevent most preterm preeclampsia in high-risk women. The risk can be estimated either by considering clinical factors or by using the Fetal Medicine Foundation (FMF) algorithm, which considers placental growth factor with blood pressure and other markers. Among nulliparous women, a low FMF risk is associated with low incidences of preeclampsia (<2.5%) and preterm preeclampsia (<0.5%), and a high FMF risk is associated with high incidences of preeclampsia (>6%) and preterm preeclampsia (>1.5%; P < 0.001), regardless of clinical risk factors. Where available, the FMF algorithm including placental growth factor should be the only tool used for preeclampsia screening.
Institutions: Centre National de la Recherche Scientifique, Inserm, Centre Hospitalier Universitaire de Toulouse, Institut Toulousain des Maladies Infectieuses et Inflammatoires, Centre de recherche du CHU de Québec-Université Laval, CHU de Québec-Université Laval, Université de Lille, Centre Hospitalier Universitaire de Lille, Université Laval, Université de Montréal, University of Toronto, University of Calgary
Language: English
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,100
OpenAlex ID: W7160644468