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Brown Tumour Mimicking Skeletal Metastasis in 68 Ga-PSMA PET/CT

Year: 2026

Type: article

Abstract: We report a case of a patient with chronic kidney disease who underwent 68 Ga-PSMA (prostate-specific membrane antigen) positron emission tomography/computed tomography (PET/CT) for suspected prostate carcinoma in the setting of equivocal multiparametric magnetic resonance imaging (MRI) findings, a suspicious bone lesion, and a negative prostate biopsy. Imaging demonstrated diffuse PSMA uptake in the prostate and PSMA-avid lytic lesion of the iliac bone, which was subsequently confirmed to represent a brown tumour secondary to renal osteodystrophy. This report highlights a previously unreported benign skeletal condition demonstrating PSMA uptake and mimicking metastatic disease.

Source: Indian Journal of Nuclear Medicine

DOI: 10.25259/ijnm_7_2026

Authors: Selvaratnam Abhilash, Shanmuga Sundaram Palaniswamy

Institution: Amrita Vishwa Vidyapeetham

Language: English

Topic: Bone Tumor Diagnosis and Treatments

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W7160697465