Work

In vivo reprogramming of cytotoxic effector CD8 T cells via fractalkine-conjugated mRNA-LNPs

Year: 2026

Type: article

Source: Science Immunology

DOI: 10.1126/sciimmunol.aec3436

Institutions: University of Pennsylvania, Emory University, Emory National Primate Research Center, Acuitas Therapeutics (Canada), The Wistar Institute

Language: English

Topic: RNA Interference and Gene Delivery

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Parker Institute for Cancer Immunotherapy, Mark Foundation For Cancer Research, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Office of Research Infrastructure Programs, National Institutes of Health

Awards: G2551296379, G3989666559, G4756012576, G5358192404, A multipronged, mRNA gene therapy approach to HIV cure, G8154987292, G9000012859, G9000077235, G9000178764, G9000201316, G9000221685, G9000299776, Combined Adult and Pediatric Infectious Disease Postdoctoral Training Grant, G9000341336

OpenAlex ID: W7160705311

FWCI:

Cites: 71

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