Nationwide Comparison of 2 year Revision Surgery Risk After Hybrid Cervical Surgery with 2-Level ACDF and 2-Level CDR Surgical Technique
Year: 2026
Type: article
Study design: Observational Study
Abstract: Study designRetrospective cohort study.ObjectiveTo perform a retrospective study comparing 2 level hybrid surgery (1 level ACDF and 1 level CDR) with 2 level ACDF and 2 level CDR.MethodsPatients undergoing first-instance two-level cervical spine surgery were identified using CPT codes and grouped into ACDF, CDR, or hybrid (single-level ACDF + single-level CDR) cohorts, with exclusions for posterior fusion, trauma, infection, malignancy, prior revision, and overlapping procedures. Revision surgery was defined as any cervical operation within two years of the index procedure, and baseline variables included demographics, comorbidities (Elixhauser Comorbidity Index), cervical pathology, insurance type, tobacco history and osteoporosis. Comparisons were performed using t-tests and chi-square tests, and adjusted Cox proportional hazards models and Kaplan-Meier analysis were used to evaluate two-year revision risk and revision-free survival among cohorts.ResultAmong 122,164 patients, ACDF patients were older and had greater comorbidity burden and higher rates of myelopathy and osteoporosis, with overall secondary cervical procedures most frequent after two-level ACDF. On multivariable analysis, myelopathy, tobacco history and osteoporosis were independently associated with increased revision risk, while insurance status was not. Surgical approach (ACDF, CDR, or hybrid) was not independently associated with two-year revision risk, and Kaplan-Meier analysis showed no significant differences in revision-free survival among cohorts.ConclusionSurgical approach (ACDF, CDR, or hybrid) was not independently associated with differences in two-year revision risk.
Source: Global Spine Journal
Institution: University of Southern California
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,650
OpenAlex ID: W7160838198