Work

Deep Learning-Based Automatic Segmentation of Ischemic Stroke Lesions in CT Perfusion Imaging

Year: 2026

Type: article

Abstract: Ischemic stroke, a major cause of global disability, is characterized by the blockage of an artery leading to reduced cerebral blood flow and subsequent brain injury. Automatic segmentation of ischemic stroke lesions in Computed Tomography Perfusion (CTP) maps is critical for accurate diagnosis, treatment planning, and outcome assessment. However, the accuracy of traditional methods remains limited, with Dice Similarity Coefficient (DSC) values around 68%. To address this challenge, we propose a deep learning-based model inspired by biological systems and brain mechanisms, which emulates natural information processing to enhance ischemic stroke lesion segmentation. The proposed network architecture consists of five graph convolutional layers that automatically extract and classify features from CTP images. We evaluated the model using the ISLES 2018 database, achieving a DSC of 75.41% and a Jaccard Index of 74.52%, representing significant improvements over previous methods. Notably, the proposed approach performs robustly in noisy environments, maintaining accuracy above 60% even at SNR = -4. These results demonstrate the potential of biomimetic-inspired networks for automatic ischemic stroke segmentation.

Source: Biomimetics

DOI: 10.3390/biomimetics11050334

Authors: Lida Zare Lahijan, Saeed Meshgini, Reza Afrouzian

Institution: University of Tabriz

Language: English

Topic: Medical Image Segmentation Techniques

Subfield: Computer Vision and Pattern Recognition

Field: Computer Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,654