Work

Formulation Development and Characterization of Novel Antipsoriatic Gel for Topical Drug Delivery Sysyem

Year: 2026

Type: article

Abstract: Studies using FTIR spectroscopy verified that the medicine and excipients are compatible. Dimethyl sulfoxide, Carbopol 10NF, propylene glycol, glycerol, methyl paraben, propyl paraben, and water were used to make the gel. Out of all the formulations, the Optimized formulation (F3) is the most effective. The prepared gel demonstrated satisfactory physical characteristics, including assay (97%w/w) and pH (4.99). Additionally, 98.2% of the medication was released in 12 hours according to in vitro diffusion experiments. For one, two, and three months, the formulation was loaded for stability at accelerated conditions of 40°C/75%RH and 30°C/65%RH. The optimized formulation (F3) has demonstrated satisfactory in vitro performance and good stability.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.20120852

Author: Prajkta Diwakar Durge*, Dr. P. M. Pimpalshende

Language: English

Topic: Advancements in Transdermal Drug Delivery

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7160855790

FWCI:

Cites:

Cited by:

Related to: