Work

Insights into Sensing and Biomedical Domains Using Multi-Synthetic Covalent Organic Frameworks

Year: 2026

Type: article

Abstract: Covalent organic frameworks (COFs) are one of the most important crystalline structures, having high porosity, and are mostly composed of lighter elements, such as H, C, N, O, etc., with covalent bonds between them. They are chemically synthesized in a repetitive arrangement and create a highly effective porous surface area that plays a fundamental role in various applications including sensing and biomedical applications. This study offers an overview of COFs in sensing and biomedical applications and provides a detailed overview of various synthesis procedures of COFs. Next, we explore their innovative sensing performances in the cases of various gases, ions and metals. Finally, it is emphasized that the major biomedical applications of COFs have been addressed regarding diseases and treatment strategies. Overall, this review offers an overview of COFs' capabilities and promising behaviors in enhancing and revolutionizing sensing and biomedical technologies.

Source: Biosensors

DOI: 10.3390/bios16050280

Authors: Hassan Imam Rizvi, Yuchen Qiao, Shilpa Dabas, Peng Ren, Xuemei Yang

Institution: Harbin Institute of Technology

Language: English

Topic: Covalent Organic Framework Applications

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $2,654

Funders: Development and Reform Commission of Shenzhen Municipality, Basic and Applied Basic Research Foundation of Guangdong Province