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Society of Interventional Radiology Position Statement on Genicular Artery Embolization for Symptomatic Knee Osteoarthritis

Year: 2026
Type: article
Abstract: Knee osteoarthritis (KOA) is a prevalent musculoskeletal condition characterized by a significant therapeutic gap between the failure of conservative medical therapies and surgical arthroplasty. Contemporary evidence supports a model in which chronic synovitis and pathologic neoangiogenesis, closely coupled to perivascular nociceptive nerve growth, serve as significant contributors of pain and peripheral sensitization in KOA. Genicular artery embolization has emerged as a targeted, joint-preserving vascular intervention performed by interventional radiologists that directly addresses the inflammatory and neurovascular components of KOA. The purpose of this societal-endorsed position statement is to synthesize the current knowledge base for genicular artery embolization and review its biologic rationale, clinical evidence, technical considerations, safety profile, and evolving regulatory landscape.
DOI: 10.1016/j.jvir.2026.108803
Authors: Osman Ahmed, Bedros Taslakian, Yuji Okuno, Peter Minko, Jafar Golzarian, Sandeep Bagla, Marc Sapoval, Mateus Picada Correa, Mark Little, Luke Wilkins, Joel A. Block, Brendon Ross, Sara Wallace, Magdalena Anitescu, Charles Ray, Siddharth A. Padia
Institutions: University of Utah, University of Miami, Heinrich Heine University Düsseldorf, University of Minnesota, Université Paris Cité, Universidade de Passo Fundo, Royal Berkshire NHS Foundation Trust, University of Virginia, Rush University Medical Center, University of Chicago, University of Chicago Medical Center, University of Utah Health Care, University of California, Los Angeles
Language: English
Subfield: Rheumatology
Field: Medicine
Open Access status: hybrid
Estimated APC paid: $3,600
OpenAlex ID: W7160945980
FWCI: 45.95
Cites: 55
Cited by: 12
Related to: 10