ONE-POT TWO COMPONENT SYNTHESIS AND INVITRO STUDY OF BENZOXAZOLE PROMOTED BY CuI2
Year: 2026
Type: article
Abstract: In this study, we present the design, synthesis, structural characterization, and biological evaluation of new benzoxazole from 2-aminophenol and substituted aldehydes in the presence of catalytic quantity of CuI2 at room temperature.as possible therapeutic agents a two-component, one-pot cyclocondensation reaction using conventionally produced methods. Using mass spectrometry, 1HNMR, and 13CNMR, all substances were described. Furthermore, the desired compound outperformed the standard antibacterial activity by exhibiting notable against important bacterial strains, streptomycin and certain of its derivatives demonstrated moderate to high antibacterial effectiveness. These findings show that benzoxazole derivatives hold substantial promise for further development as medicinal agents.
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
OpenAlex ID: W7161350259
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