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Additional file 11: Figure S10. of EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth

Year: 2017

Type: article

Abstract: Cell growth kinetics in 2D cultures of human breast cancer cell lines after SPOCK1 silencing. A. Analysis of SPOCK1 expression levels by RT-qPCR in human cells transduced with a scramble shRNA (shControl) and two different shRNAs (shSPOCK#1 and shSPOCK#2) targeting human SPOCK1. B. MTS in vitro proliferation assay of MDA-MB-231 (top), 1833 (middle), and BT549 (bottom) cells. Data were normalized with absorbance values from day 0 and represent mean ± SD of six replicates. Experiments were repeated three times with similar results. C. Percentage of MDA-MB-231 (top), 1833 (middle), and BT549 (bottom) cells in each phase of the cell cycle, after maintaining cells in culture for 24 and 48 h. (PPTX 223 kb)

Source: Figshare

DOI: 10.6084/m9.figshare.4569145

Authors: Perurena, Naiara, Zandueta, Carolina, Martínez-Canarias, Susana, Moreno, Haritz, Vicent, Silvestre, Almeida, Ana, Guruceaga, Elisabet, Gomis, Roger, Santisteban, Marta, Egeblad, Mikala, Hermida, José, Lecanda, Fernando

Language: English

Topic: Cancer Cells and Metastasis

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7161394623

FWCI:

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