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Enzyme-Triggered Charge and Conformation Switching for Tumor-Selective Peptide–Drug Conjugates

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Year: 2026
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.6c00326
Authors: Jiaying Wei, Qipeng Yan, Xingyue Jiang, Wei Xie, Min Wei, Yuan Dan, Xia Wu, Junfeng Shi
Institutions: Hunan University, State Key Laboratory of Chemobiosensing and Chemometrics
Language: English

Topic: Nanoparticle-Based Drug Delivery
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Science and Technology Foundation of Shenzhen City, National Natural Science Foundation of China, Natural Science Foundation of Guangdong Province, Natural Science Foundation of Hunan Province
Awards: 响应GGT的细胞选择性穿膜肽的研究及应用, G2994961967, G3299233263, G5555987510, G5739087220, 酶响应型多肽偶联药物的设计合成及其抗肿瘤应用研究, G6633148472, G6987830599, G8148879417
OpenAlex ID: W7161421936
FWCI:
Cites: 58
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