Marked Improvement of Chronic Motor and Phonic Tics With Cariprazine in an Adult With Tourette Syndrome With Comorbid Bipolar Disorder: A Case Report
Year: 2026
Type: article
Study design: Case Report
Abstract: Tourette syndrome (TS) is a neuropsychiatric disorder characterized by motor and phonic tics, often complicated by comorbid conditions and treatment-related adverse effects. We report a 61-year-old male with long-standing TS and comorbid bipolar disorder who experienced persistent, functionally impairing tics despite multiple prior therapies. Following initiation and titration of cariprazine, the patient demonstrated marked and sustained improvement in tic severity over approximately two years, with good tolerability and stable mood symptoms. This case highlights a potential role for cariprazine in the management of tic disorders in patients with complex neuropsychiatric comorbidities.
Source: Cureus
Authors: Gavin L Feinberg, George Burton, Jennifer J Hawkins, Jorge L Juncos
Institutions: Augusta University, Billings Clinic, Emory University
Language: English
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Open Access status: diamond
OpenAlex ID: W7161493092