Appendiceal Neuroendocrine Tumor: A Case Report
Year: 2026
Type: article
Study design: Case Report
Abstract: Neuroendocrine tumors (NETs) are rare neoplasms that most commonly occur in the gastrointestinal tract, lungs, and pancreas but may arise anywhere where there are neuroendocrine cells within the body. When neuroendocrine tumors metastasize to the liver, patients present with carcinoid syndrome, a group of symptoms characterized by flushing, diarrhea, and right-sided heart disease. However, many NETs do not cause carcinoid syndrome, sometimes leading to a unique clinical presentation. Patients may present with symptoms of appendicitis, ovarian torsion, or be completely asymptomatic. We report a case of a 25-year-old male with a Grade 1 neuroendocrine tumor of the appendix, who underwent a laparoscopic appendectomy. Determining whether the NET has metastasized is crucial for proper long-term treatment of patients post-appendectomy.
Authors: Daniel Zipfel, Thomas Russo, Mathew Devine
Institution: Lake Erie College of Osteopathic Medicine
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7161542070
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