Work

Control of genes by self-organizing multicellular interaction networks

Year: 2026

Type: article

Abstract: Multicellular self-organization drives development in biological organisms, yet a comprehensive theory is lacking as basic properties of cells can complicate common approaches. Framing such properties by dynamic graphs led to new theoretical propositions for multicellular self-organization in Escherichia coli. Here, corresponding ideas are developed from biologically-general first principles. The resulting perspective could aid both experimental and computational approaches to multicellular biology as well as efforts to control and engineer it.

Source: npj Systems Biology and Applications

DOI: 10.1038/s41540-026-00745-9

Author: Kyle R. Allison

Institution: Emory University

Language: English

Topic: Gene Regulatory Network Analysis

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $3,490

OpenAlex ID: W7161550692

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