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Electroenzymatic Oxidative Desymmetrization by Engineered Thiamine-Dependent Enzymes for the Enantioselective Synthesis of Axially Chiral Biaryls

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Year: 2026
Type: article
Source: Journal of the American Chemical Society
DOI: 10.1021/jacs.6c01275
Authors: Fengming Shi, Yingzhi Ren, Jiayu Wu, Jinhai Yu, Beibei Zhao, Bin Chen, Aokun Liu, Yue Zhao, Lu Yu, Yan Zhang, Xiaoqiang Huang
Institutions: Nanjing University, University of Science and Technology of China
Language: English

Topic: Enzyme Catalysis and Immobilization
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: closed

Funders: National Natural Science Foundation of China, Ministry of Education of the People's Republic of China, National Key Research and Development Program of China, Fundamental Research Funds for the Central Universities
Awards: G1207702473, G3151371060, G3762305802, G3812517105, G4067216149, G8719275527
OpenAlex ID: W7161593439
FWCI: 5.466
Cites: 80
Cited by: 3
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