Work

Whole-genome sequence of a varicella-zoster strain from an immunocompetent pediatric patient with severe herpes zoster

Year: 2026

Type: article

Abstract: We report the complete genome sequence of CGI, a strain of varicella-zoster virus (VZV) isolated from a 3-year-old immunocompetent patient with severe herpes zoster. The isolated strain exhibits an ORF62 genotype characteristic of vOka, in addition to a wild-type ORF0 gene and a novel methionine to valine substitution in ORF58.

Source: Microbiology Resource Announcements

DOI: 10.1128/mra.01123-25

Authors: Alejandro Ortigas-Vasquez, Braylen V. Washington, Mackenzie Shipley, David C. Bloom, Charles Grose, Moriah L. Szpara

Institutions: Pennsylvania State University, University of Florida, University of Iowa

Language: English

Topic: Herpesvirus Infections and Treatments

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Pennsylvania Department of Health, National Institutes of Health, National Science Foundation of Sri Lanka, National Institute of Allergy and Infectious Diseases