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Human pancreatic progenitor organoids define genetic and epigenetic barriers to early PDAC transformation

Year: 2026
Type: article
DOI: 10.1016/j.devcel.2026.04.012
Authors: Xian Zhang, Wilfred Wong, Hyein S. Cho, Dapeng Yang, Gary Dixon, Renhe Luo, Dingyu Liu, Denis Torre, Shigeaki Umeda, Federico González, Gokce Askan, Aslihan Yavas, Jeyaram Ravichandran Damodaran, Robert W. Rickert, Rajya Kappagantula, Fong Cheng Pan, Victoria G. Aveson, Adrien Grimont, William B. Fall, Xianming Wang, Julian Pulecio, Samuel J. Kaplan, Heng Pan, Xianlu Laura Peng, Jen Jen Yeh, Steven D. Leach, Christine A. Iacobuzio-Donahue, Rohit Chandwani, Christina S. Leslie, Danwei Huangfu
Institutions: Memorial Sloan Kettering Cancer Center, Weill Cornell Medicine, Cornell University, Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences, University of North Carolina at Chapel Hill, UNC Lineberger Comprehensive Cancer Center, Dartmouth College
Language: English
Subfield: Oncology
Field: Medicine
Open Access status: green
Funders: Geoffrey Beene Cancer Research Center, Cycle for Survival, National Institutes of Health, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases, Eunice Kennedy Shriver National Institute of Child Health and Human Development
OpenAlex ID: W7161636989
FWCI: 5.484
Cites: 97
Cited by: 2
Related to: 10