CT of Soft Tissue Infections: Current and Future Perspectives from Diagnosis to Treatment
Year: 2026
Type: article
Abstract: Background/Objectives: Skin and soft-tissue infections represent a critical diagnostic challenge in the emergency department, requiring rapid differentiation between superficial processes and life-threatening necrotizing conditions. Methods: This clinical update analyzes the central role of CT in the assessment of these pathologies, proposing a management-oriented algorithm to support risk stratification and therapeutic planning. Results: By reviewing the fundamental semiological features of contrast-enhanced CT, this work highlights how the identification of critical markers directly guides the choice between medical management and urgent surgical intervention. In addition to consolidating protocols based on conventional CT, the article examines current perspectives and clinical limitations of emerging technologies, including Spectral CT (DECT and PCD-CT) and artificial intelligence, evaluating their potential to improve image quality and tissue characterization. Conclusions: In conclusion, while technological evolution offers new diagnostic frontiers, a rigorous and systematic interpretation of CT findings remains the fundamental pillar for optimizing patient outcomes and reducing unnecessary interventions.
Source: Journal of Clinical Medicine
DOI: 10.3390/jcm15103915
Institutions: IRCCS Azienda Ospedaliera Metropolitana, University of Genoa
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,137
OpenAlex ID: W7161638215
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