Hybrid Nanocrystalline Theranostic Agents Designed for Magnetic Resonance Imaging, Photothermal, and Photodynamic Therapies Against Cancer
Year: 2026
Type: article
Abstract: ABSTRACT Photodynamic therapy (PDT) is a promising, effective, and non‐invasive treatment for superficial cancers, utilizing reactive oxygen species (ROS) generated by induced light‐irradiated photosensitizers (PS) to provoke cancer cell death. Photothermal therapy (PTT) on the other hand, relies on heat generation by light‐irradiated PS for effective thermal cancer treatment. Both treatments have limitations when applied individually; however, a synergistic approach combining both PDT and PTT could overcome these shortcomings. Protoporphyrin (PpIX) is an effective and widely used PS for PDT but in its molecular form, its application is hindered by significant biopharmaceutical drawbacks, such as high hydrophobicity.
Source: Nano Select
DOI: 10.1002/nano.70123
Institutions: Centre National de la Recherche Scientifique, Chimie ParisTech - PSL, Université Paris Sciences et Lettres, Institute of Chemistry for Life and Health Sciences, Inserm, Université Paris Cité, Unité de Technologies Chimiques et Biologiques pour la Santé, Sorbonne Université, Laboratoire d’Imagerie Biomédicale, PHENIX laboratory, Laboratoire de Physique et d’Étude des Matériaux
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $2,660
Award: G3552746525
OpenAlex ID: W7161710547