Work

Electric field-dependent excited-state twisting in donor–acceptor thiazolothiazole dyes establishes a new class of cell membrane voltage sensors

Year: 2026

Type: article

Abstract: The underlying mechanism behind the voltage sensing ability of thiazolothiazole fluorophores has been revealed through the characterization and computational analysis of several newly developed cell membrane probes.

Source: Chemical Science

DOI: 10.1039/d6sc04210d

Authors: Pranamita Chakraborti, Rui Fu, Lucia M. Wert, Charlie A. L. Darby, Joy D. Amuzu, Daphne Oettinger, Aditya Nandy, Yamuna Krishnan, Michael G. Walter

Institutions: University of North Carolina at Charlotte, University of Chicago, University of California, Los Angeles

Language: English

Topic: Molecular Sensors and Ion Detection

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funders: National Science Foundation, University of North Carolina, Human Frontier Science Program, National Institutes of Health, National Institute of General Medical Sciences, National Institute of Neurological Disorders and Stroke

Awards: G1530426707, G180487808, Calcium homeostasis in organelles, G5919435044, Synthesis and Exploration of Highly Fluorescent Thiazolothiazole Molecular Sensors for Probing Membrane Potential Dynamics, Synthesis and Exploration of Highly Fluorescent Thiazolothiazole Molecular Sensors for Probing Membrane Potential Dynamics, G9000383276, Intracellular Electrophysiology: An electrochemical atlas of organelles, REU Site: Nanoscale Science Undergraduate Research Experience (NanoSURE) at UNC Charlotte

OpenAlex ID: W7161828230

FWCI:

Cites: 47

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Related to: 10