A prospective cohort study comparing IADPSG and DIPSI criteria for diagnosing gestational diabetes and evaluating impact on maternal and neonatal health outcomes (DECIDE study protocol)
Year: 2026
Type: article
Study design: Study Protocol
Abstract: BACKGROUND: Accurate diagnosis of gestational diabetes mellitus (GDM) is important for improving the short and long-term outcomes of mothers and babies. There are different criteria to diagnose GDM. Around the world, many use the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria. However, in India, a different method called the Diabetes in Pregnancy Study Group of India (DIPSI) criteria is more commonly used. However, there is limited evidence comparing how well these two criteria work in improving pregnancy outcomes for Indian women. This study aims to fill that gap by looking at the pregnancy outcomes of women who are diagnosed with GDM using the IADPSG method but are considered normal by the DIPSI method. METHODOLOGY: The DECIDE (Diagnostic Evaluation and Comparison of IADPSG and DIPSI criteria for expectant mothers) study is a prospective, multicenter observational cohort study being conducted across seven sites in India, enrolling pregnant women 18 years or older and between 24 to 28 weeks of pregnancy. Two glucose tests are conducted as part of this study. The first test follows the DIPSI method, which does not require fasting beforehand. The second test follows the IADPSG method, which requires fasting overnight and measures blood glucose levels three times, before drinking a glucose solution, one hour after, and two hours after. The results of the IADPSG test are kept blinded from the treating physician and the participant, unless the woman is found to have very high blood glucose levels (overt diabetes). Postdelivery, pregnancy outcomes of both the mothers and their newborns are collected using medical records and lab reports. DISCUSSION: This study aims to address the ongoing debate about the effectiveness of two diagnostic criteria for gestational diabetes: DIPSI and IADPSG. The goal is to determine whether the higher costs and complexity of adopting the IADPSG criteria are justified by better maternal and neonatal outcomes. The findings are expected to provide valuable insights that could help shape national guidelines on appropriate diagnostic criteria for GDM that can help in improving the health of mothers and newborns in India.
Source: BMC Pregnancy and Childbirth
Authors: Yashdeep Gupta, Nomita Chandhiok, Reema Mukerjee, Shrinivas N.Gadappa, Ashish V. Gokhle, M. Geetha, Ramesh Sonowal, Anjoo Agarwal, Jyotsna Suri, Sarita Agrawal, Kalaivani Mani, Neerja Bhatla, Nikhil Tandon, DECIDE, Sonali Deshpande, Rupali Gaikwad, Rupali Gaikwad, Purvi K Patel, Sonali Agarwal, A Suganya, T Uma, T S Meena, K Kalaivani, G Kuppulakshmi, C Sumathi, Pulak Kalita, Aukifa K S Islam, Ajit Kr Pegu, Rashmi Rajkakati, Amita Pandey, Vandana Solanki, Shalini Tripathi, Vandana Solanki, Mohd Kaleem Ahmad, Sumitra Bachani, Krishna Biswas, Anita Rani, Pradeep Debata, Nilaj Kumar Bagde, Amritava Ghosh, Rachita Nanda, Atiya Raza, Maitreyi Dhir, Akanksha Verma, Prachi Tewari, Mugdha Ratnaparkhi, Jayesh Parmar, Arvind Bharani, Rashi Sonowal, Kritika Jain, Seema Kush, Mr N Sai Pawan
Institutions: All India Institute of Medical Sciences, Indian Council of Medical Research, Government Medical College, Sir Sayajirao General Hospital Medical College, Assam Medical College, King George's Medical University, Safdarjang Hospital, Vardhman Mahavir Medical College & Safdarjung Hospital, All India Institute of Medical Sciences Raipur
Language: English
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,290
OpenAlex ID: W7161960637