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Plasma cell myeloma-related serous cavity effusion: Cytological and clinical insights from two cases

Year: 2026

Type: article

Abstract: Disseminated plasma cell myeloma is an uncommon phenomenon and is characterized by a disease biology that is distinct from medullary disease. These are characterized by high-risk cytogenetic abnormalities and aggressive disease course. Involvement of body fluids by plasma cell dyscrasias poses a diagnostic challenge owing to morphological overlap with other reactive or clonal conditions. Clinical history, along with diagnostic adjuncts such as flow cytometry, cell block, and immunohistochemistry, is an essential tool for comprehensive evaluation, diagnosis, and eventual therapeutic decision-making. We discuss two cases of body fluids involved in plasma cell dyscrasia along with relevant diagnostic dilemmas and review of literature.

Source: Journal of Hematology and Allied Sciences

DOI: 10.25259/jhas_72_2025

Authors: Sudhanya Biswas, Anirban Kundu, Atoshi Basu

Language: English

Topic: Multiple Myeloma Research and Treatments

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W7162006592

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Cites: 9

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