Work

Dataset for 'Intranasal boosting induces variant-specific responses in SARS-CoV-2 vaccine-imprinted mice'

Year: 2026

Type: dataset

Abstract: This dataset contains the raw data supporting main Figures 1-5 and Extended Data Figures 1-10 used in the manuscript "Intranasal boosting induces variant-specific responses in SARS-CoV-2 vaccine-imprinted mice" submitted to Nature Communications. The dataset includes antibody titers in the serum and bronchoalveolar lavage fluid of mice immunized with SARS-CoV-2 mRNA or chimpanzee adenoviral-vectored vaccines at various regimens. The dataset also includes pseudovirus neutralization results and flow cytometry analysis of vaccinated mice. Vaccinations were conducted in wild-type C57BL/6J mice or animals expressing human ACE2 (K18-hACE2 mice). Neutralization assays were performed using Vero cells overexpressing TMPRSS2.

Source: Mendeley Data

DOI: 10.17632/9drz7yrmny

Authors: Liang, Chieh-Yu, Scheaffer, Suzanne M., Case, James Brett, Dmitriev, Igor P., Li, Yuhao, Malladi, Sameer Kumar, Liu, Xinyi, Ying, Baoling, Desai, Pritesh, Whelan, Sean P.J., Curiel, David T., Ellebedy, Ali H., Diamond, Michael

Institution: Washington University in St. Louis

Language: English

Topic: SARS-CoV-2 and COVID-19 Research

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Allergy and Infectious Diseases

OpenAlex ID: W7162067971

Cites:

Cited by:

Related to: 10