Redox protection by bacterial glutathione peroxidase drives virulence in Pseudomonas aeruginosa
Year: 2026
Type: article
Abstract: BACKGROUND: relies on antioxidant enzymes to withstand host-derived oxidative stress during infection. Here, we investigated the role of bacterial glutathione peroxidase (GPx) in survival and virulence of the PA14 strain under inflammatory conditions associated with hyperuricemia. METHODS: strains to assess bacterial burden, inflammation, oxidative damage, and survival. RESULTS: resistance to oxidative killing and promoting virulence. CONCLUSION: .
Source: Redox Report
Authors: Jadye da Silva Cordeiro, Thiago Macêdo Lopes Correia, Igor Pereira Ribeiro Muniz, Railmara Pereira da Silva, Talita Costa dos Santos, Leonardo Silva Rocha, Regiane Yatsuda, Julia de Oliveira Borges, Albert Souza Peixoto, Amélia Cristina Mendes de Magalhães, Robson Amaro Augusto da Silva, Flávia Carla Meotti, Raphael Ferreira Queiroz
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,993
OpenAlex ID: W7162114018